Genetic markers and duodenal ulcer.

Study of duodenal ulcer disease in 100 families using total serum pepsinogen as a genetic marker.

Although various markers have been used in attempts to elucidate the mode of inheritance of duodenal ulcer, they have not significantly contributed to a clear understanding of the problem. In the present study total serum pepsinogen was used as a genetic marker and its concentrations were estimated in 100 ulcer patients and their family members up to three generations. Eighty three per cent of ...

Serum pepsinogen, a genetic marker in duodenal ulcer.

Secretor status as a genetic marker in duodenal ulcer--a comparative study.

It has long been established that various human body secretions like saliva, semen, gastric juice contain blood group antigens. The individuals whose body fluids other than blood contain blood group antigens are known as secretors whereas the rest are nonsecretors. The secretor status of an individual is a genetically controlled factor. The role of genetic factors in the pathogenesis of duodena...

Polymorphism of alpha-1-antitrypsin and association of S and Z alleles with duodenal ulcers

Background: Duodenal ulcers are mucosal erosions that penetrate into the muscularis propria of the duodenum. They are a result of an imbalance between aggressive and defensive factors. Various environmental factors like Helicobacter pylori infection, addictions to smoking and alcohol etc. and genetic factors have been reported to be associated with duodenal ulceration. Alpha-1-antitrypsin was s...

Antiulcerogenic Effect of Zataria multiflora Boiss. on Cysteamine Induced Duodenal Ulcer in Rats

       Research advances during recent years offer new insight into therapy and the prevention of gastrointestinal ulcers by using medicinal plants. Flavonoids, tannins, triterpenoids, fatty acids and essential oils are among the most effective herbal constituents that have potential antiulcerogenic properties, and most of them could be found in Zataria multiflora. Z. multiflora</e...